Does GSG cross the blood-brain barrier?
In vivo studies show GSG has ≤0.01% BBB permeability (vs 0.03-0.05% for standard steviol glycosides) due to increased molecular size from glucosylation, confirmed by LC-MS/MS analysis of cerebrospinal fluid in primate models.This article was published on March 20, 2026, and last updated on March 20, 2026. The article will be continuously updated.