What makes Reb M’s glycosylation pattern unique?

Reb M contains three β-D-glucosyl units (vs two in Reb A/D) with 1→2 and 1→6 linkages at C-13/C-19 positions. This triple-glycosylation gives it 500-550× sucrose sweetness (vs 350× for Reb A) and reduces bitterness threshold to ≤0.15ppm.

This article was published on March 20, 2026, and last updated on March 20, 2026. The article will be continuously updated.